Dr. Ross Chapman

Biography

Ross Chapman started his research career in 2002 as a Research Assistant at the MRC Genome Damage Stability Centre at the University of Sussex, UK. In 2006, he joined Professor Steve Jackson’s laboratory at the Gurdon Institute, Cambridge for his PhD research, focusing on the regulated assembly of DNA repair signaling complexes at DNA break sites. After serving as a Sir Henry Wellcome Fellow, he continued with a short postdoc in Jackson's laboratory until 2010, when he joined Professor Simon Boulton’s lab at Cancer Research UK Clare Hall Laboratories. His research has examined the interplay between non-homologous end joining and homologous recombination DNA repair pathways, the role of the immune system in development, and responses to cancer therapy. In 2013, he established his group at the Wellcome Centre for Human Genetics in the Nuffield Department of Medicine, University of Oxford, and was elected Associate Professor in 2017. In 2020, his laboratory relocated to the MRC Molecular Haematology Unit in Oxford. Chapman is a holder of Cancer Research UK Lister Institute Fellowships and is a member of the EMBO Young Investigator Programme. His group focuses on genetic recombination mechanisms, particularly the major DNA double-strand break repair pathways, and aims to develop innovative strategies that exploit faults in these mechanisms for cancer therapies.

Research Interests