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Rudolf Jaenisch is a Professor in the Department of Biology at the Massachusetts Institute of Technology and a Core Member of the Whitehead Institute. His research focuses on the use of pluripotent cells, including embryonic stem cells and induced pluripotent stem cells, to study the genetic and epigenetic basis of human diseases such as Parkinson’s disease, Alzheimer’s disease, autism, and cancer. His work aims to understand the epigenetic regulation of gene expression in mammalian development and disease, recognizing the importance of embryonic stem cells in regenerative medicine. Jaenisch and his lab investigate how somatic cells can be reprogrammed to an embryonic pluripotent state and utilize patient-specific pluripotent cells to explore complex human diseases.