Professor Dr. Ruth Montgomery

Biography

Ruth R. Montgomery is a cellular immunologist with a particular expertise in the use of novel technology for human translational studies. Her research employs system-wide studies to identify individual differences in immune responses that lead to divergent outcomes in infections. Her group focuses on the effects of aging and innate immunity, investigating individual variations that influence susceptibility to viruses such as West Nile, dengue, Zika, and COVID-19, as well as inflammatory profiling in patients with sickle cell disease. Over her career, she has overseen studies of immune responsiveness in human cohorts, successfully enrolling over 2000 healthy individuals. Dr. Montgomery's notable work utilizes primary human cells to demonstrate immune-related mechanisms, illuminating potential avenues for therapeutic interventions. She launched the CyTOF facility at Yale in 2013, co-chairs the University Provost’s Advisory Committee (ITSAC), and serves as the Associate Dean for Scientific Affairs in the Yale School of Medicine.

Research Interests