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The Ruthen Lab is focused on the elucidation of molecular mechanisms underlying genome management, employing toolkits in biochemistry and chemical structural biology. The research spans traditional disciplines, emphasizing the interplay between chromatin structure and transcriptional regulation. The lab's projects aim to transition from biological discovery to in-depth molecular structural investigation, particularly concerning post-translational modifications and noncoding RNA's roles in chromatin architecture. With these interests, the team engages in various collaborative efforts and projects that probe the regulatory dynamics of chromatin states and their implications for cellular identity and function.
Department of Philosophy