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Sabrina Leslie is an Associate Professor in the Department of Physics at the University of British Columbia. Her research focuses on single-molecule biophysics, particularly investigating the dynamics of DNA and RNA protein interactions. Dr. Leslie's team develops tools for single-molecule and single-cell imaging and analysis, contributing to the understanding of biophysical properties of molecules and cells within therapeutic contexts. Her work aims to enhance the quantification of molecular interactions and guide the rational design of therapeutic molecules for genetic medicine. Notable research projects include elucidating mechanisms behind antisense oligonucleotides and protein-protein interactions, as well as the biophysical properties of nucleic acid hybridization. She leads the Leslie Lab located within the Michael Smith Laboratories, collaborating with interdisciplinary teams to advance health sciences through innovative research.
University of British Columbia • Vancouver, Canada
Joint appointment in the Department of Physics and Michael Smith Labs.
McGill University • Montreal, Canada
Harvard University • Cambridge, USA
Worked in Chemistry & Chemical Biology under Adam Cohen.
Offers course-only and thesis routes. Focus areas include philosophy of science, mind, ethics, and Asian philosophy.