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Salvatore Vincent Pizzo is a Professor Emeritus at Duke University, specializing in Pathology. His research primarily focuses on the molecular chaperone GRP78 and its role in prostate cancer malignancies. Studies from his lab have identified GRP78 as a critical factor that functions as a signaling receptor, promoting tumor proliferation while suppressing apoptosis. Pizzo's findings suggest that patients with malignancies may mount an autoimmune response against GRP78 antibodies, which can bind to specific domains of GRP78, indicating a poor prognosis. His academic journey includes leadership in the Cell Biology and Biochemistry Program at Duke University and extensive training in Pathology. Pizzo has received numerous grants, notably for his work on early biomarkers for radiation-induced heart disease and novel antibody treatments for fibrotic diseases. His dedication to advancing cancer research has earned him recognition in the field.
Duke University • Durham, NC
Specializes in Pathology and leads research on the GRP78 chaperone's role in cancer.
Department of Biomedical Engineering (MS program)