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Sam Butterworth is a Professor of Medicinal Chemistry at the University of Manchester, having joined the institution as a Senior Lecturer in November 2016 and subsequently promoted to Professor in 2024. Prior to his current role, he worked at the University of Birmingham from 2013 and at AstraZeneca from 2005 to 2013. His contributions at AstraZeneca included the development of the targeted anti-cancer agent AZD9291, known internationally as osimertinib or Tagrisso, which was approved by the FDA in November 2015. Sam’s research focuses on synthetic biological chemistry and its applications in solving biological problems that are relevant to human health and disease. He has collaborated with biomedical researchers and clinicians to test compounds in relevant biological models, and his work is aligned with the UN Sustainable Development Goals aimed at ending poverty and protecting the planet. His research interests primarily include Medicinal Chemistry and Pharmacology.
University of Manchester • Manchester, ENG, GB
Leading research in Medicinal Chemistry and developing anti-cancer therapeutics.
University of Manchester • Manchester, ENG, GB
Teaching and conducting research in Medicinal Chemistry.
AstraZeneca • Birmingham, ENG, GB
Worked in drug discovery and development, focusing on anti-cancer agents.
Includes MSc in Advanced Electrical Power Systems and MSc in Communications and Signal Processing.