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Samantha Weaver is an Assistant Professor at the University of Wisconsin-Madison, affiliated with the Stem Cell & Regenerative Medicine Center. Her research focuses on musculoskeletal conditions, which are a leading cause for doctor visits. Dr. Weaver's laboratory investigates the molecular mechanisms that regulate bone and cartilage development and disease, with the long-term goal of validating novel treatment targets and testing new therapies for conditions such as osteoporosis and osteoarthritis. Her work addresses the wide prevalence of musculoskeletal disorders and the ongoing challenge of regenerating bone and cartilage once lost. Utilizing transgenic mice and surgical induction of orthopedic disease in animal models, along with in vitro cell culture and cutting-edge imaging, her lab probes the molecular cues underlying musculoskeletal development and disease. Dr. Weaver also studies natural life events associated with extensive bone turnover and cartilage loss, including pregnancy, lactation, menopause, and aging. Her ultimate goal is to develop strategies that prevent extensive bone and cartilage loss and to discover new therapeutics that aid in tissue regeneration.
Department: Department of Computer Sciences