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Sara Buhrlage is an Associate Professor in the Department of Biological Chemistry and Molecular Pharmacology at Dana-Farber Cancer Institute and Harvard Medical School. Her research focuses on the dysregulation of protein homeostasis and its implications in various diseases, including cancer and neurodegeneration. Dr. Buhrlage's work emphasizes the role of the ubiquitin-proteasome system in maintaining proteostasis by regulating the reversible post-translational addition of polyubiquitin chains to proteins, which tags substrates for degradation. She aims to develop first-in-class inhibitors to pharmacologically validate members of the ubiquitin gene family as new targets for cancer treatment and other diseases.
Dana-Farber Cancer Institute • Boston, MA
Leading research on protein homeostasis and the role of ubiquitin in diseases.
Administered by the Division of Medical Sciences (DMS). GRE is not required and will not be considered for BBS, Immunology, and Neuroscience.