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Sarah Cobey is a Professor at the University of Chicago, where she leads a research group focused on coevolution between pathogens and hosts’ adaptive immunity. Her work utilizes computational and mathematical tools to test hypotheses and advance theory in the field of evolutionary dynamics, particularly regarding immune-mediated competition among pathogen strains such as pneumococcus and influenza. Her research emphasizes the dynamics of host immune responses and investigates how history, chance, vaccination, and host genetics influence B cell responses over time. Through her studies, she aims to link epidemiological and immunological observations to the genetic evolution of influenza viruses. An essential part of her work includes studying the effects of vaccination strategies in relation to diverse immune histories across different populations. With a focus on predictive modeling, Cobey seeks to better understand and predict coevolutionary processes, ultimately contributing to improved vaccination strategies for complex infectious diseases.
Department of Philosophy