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Sarah E. Cobey is a Professor in the Department of Ecology and Evolution at the University of Chicago. Her research primarily focuses on B cells, coevolution, and infectious disease dynamics, especially in the context of influenza. Cobey employs computational and mathematical modeling to test hypotheses and advance the theory around immune-mediated competition among pathogen strains, including the pneumococcus and human papillomavirus. She investigates the evolution of antibody repertoires and how infection history, vaccination, and host genetics contribute to the diversity of B cell responses. In her work, she links epidemiological and immunological observations to understand the genetic evolution of influenza viruses. Additionally, she focuses on the dynamics of vaccination, aiming to improve strategies considering diverse host immune histories and the potential rapid evolution of pathogens. Her goal is to sufficiently explain coevolution to enable reliable predictions regarding infectious disease dynamics.
Harvard School of Public Health • Cambridge, MA
Conducted research on infectious disease dynamics.
Department of Philosophy