Generate a tailored SOP for Dr. Sarah Hill. Improve your application with a focused, well-structured draft.
Sarah Hill is an Assistant Professor in the Biological Biomedical Sciences PhD Program at Dana-Farber Cancer Institute. Her research focuses on the role of the BRCA1 tumor suppressor protein in DNA damage repair and cancer susceptibility, particularly in breast and ovarian cancers. The lab investigates how BRCA1 protein complexes interact with DNA replication processes to prevent stalled replication forks and analyze the consequences of BRCA1 deficiencies, including cellular transformation leading to pre-malignant and malignant states. The lab employs a variety of model systems, including established cell lines, patient-derived organoid models, and mouse models, to gain insights into the functional defects of BRCA1 in cancer. The goal of her research is to leverage fundamental biological understanding of BRCA1-related functions to develop methods for the detection, prevention, and treatment of breast, ovarian, and endometrial cancers.
Administered by the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences (GSAS).