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Sarah Hughes is a Professor in the Department of Medical Genetics at the University of Alberta. Her research focuses on the molecular mechanisms linking cell polarity, proliferation, and differentiation, with a specific emphasis on how dysregulation of these processes contributes to developmental disorders and cancer. Hughes utilizes Drosophila melanogaster as a genetic model to investigate Neurofibromatosis Type 2, Schwannomatosis, and Atypical Rhabdoid Tumours. Through various methodologies including molecular biology, advanced microscopy, proteomics, and genetic analyses, her lab aims to identify and characterize the interacting proteins and cell signaling pathways that underlie these disorders. Hughes has published numerous studies that explore the roles of chromatin remodeling and protein localization in neural development, and she continues to mentor graduate students and technicians in her lab, fostering an environment focused on innovative research.
University of Alberta • Edmonton, AB
Conducts research and teaches in the field of Medical Genetics.
Department: Mechanical Engineering and Engineering Management