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Sarah Tishkoff is the David Lyn Silfen University Professor at the University of Pennsylvania. Her research expertise is in African Integrative Evolutionary Genomics, where she combines fieldwork, laboratory work, and computational approaches to address fundamental questions about modern human evolutionary history and the genetic architecture of traits related to adaptation and disease risk in Africa. Tishkoff’s work includes studying the genetic diversity among ethnically diverse Africans and identifying genetic and environmental factors affecting various traits. She aims to reconstruct the historical demographic events and test hypotheses about modern human origins, including the investigation of genetic adaptations to local environments. Tishkoff collaborates with African colleagues to analyze genomic data from unique sample sets, contributing to the understanding of genetic variation and its implications for public health issues, including infectious diseases prevalent in African populations. Additionally, her laboratory focuses on identifying significant genetic variations related to resistance to infectious diseases like malaria, TB, and HIV.
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