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Sashko Damjanovski is an Associate Professor in the Department of Biological and Geological Sciences at Western University. His research focuses on the role of secreted enzymes in regulating cell migration, invasion, and cell-cell interactions. The Damjanovski lab utilizes cultured cell models to investigate how matrix metalloproteinases (MMPs) and their inhibitors, including tissue inhibitors of metalloproteinases (TIMPs) and RECK, contribute to developmental processes and the pathogenesis of cancer. The lab employs a diverse range of cellular and molecular techniques to elucidate the regulation of MMPs during development and in disease contexts. Equipped with advanced imaging and molecular biology tools, the lab conducts various experiments, including PCR, Western blotting, and specific MMP studies like zymography, migration, and invasion assays in 3D cell culture. Damjanovski's work contributes to a deeper understanding of the molecular mechanisms influencing cell behavior in normal and pathological states.
Streams include Archaeology and Bioarchaeology, and Sociocultural Anthropology.