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Sathish Kumar’s laboratory investigates the effects of environmental chemical exposure, unbalanced diet, hormonal disruption, cigarette smoking, sleep apnea (hypoxia), and infections during pregnancy on the long-term health of mothers and babies. The lab utilizes rat models and human samples to examine how adverse prenatal exposures reprogram fetal organs such as the pancreas and skeletal muscle, which can lead to the development of diabetes in adulthood. Further, the laboratory studies the differences in metabolic functions between males and females. The long-term goal is to identify endocrine disruptors, environmental pollutants, and lifestyle disorders that contribute to metabolic dysfunctions, ultimately establishing ameliorative strategies to preserve metabolic function and develop sex-specific treatment strategies for diabetes.
Department: Department of Computer Sciences