Generate a tailored SOP for Dr. Savas Tay. Improve your application with a focused, well-structured draft.
Savas Tay is a systems biologist and bioengineer working at the intersection of biology, physics, and engineering. His overarching goal is to understand how biological systems function from an engineer’s perspective and to use this knowledge to manipulate cellular pathways to assist in curing diseases. His lab focuses on developing high-throughput, high-content single-cell analysis devices that integrate microfluidics, computation, and optics. The Tay Lab has pioneered a single-cell proteomics method that enables the concurrent measurement of proteins, protein complexes, and mRNA in thousands of individual cells. Tay's main research focus is on the dynamics of molecular pathways that govern cellular information processing, pathogen sensing, and recognition, as well as cellular communication. The lab conducts precision dynamic measurements of living cells and develops predictive models for complex systems like the immune response. These models serve as rapid test beds for drug studies and genomic perturbations. Tay is particularly interested in translating these technologies into real-world biomedical applications, evidenced by his significant contributions to the understanding of NF-κB, a crucial transcription factor regulating numerous immune genes, and how cells respond to signaling in a digital-like manner.
Pritzker School of Molecular Engineering • University of Chicago
Professor and Director of Biological Immuno Engineering Research Theme, focusing on developing technologies for high-throughput single-cell analysis.
Department of Philosophy