Dr. Scott Manalis

Professor

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Biography

Scott Manalis has been a faculty member at the Massachusetts Institute of Technology (MIT) since 1999. He develops microfluidic technologies for measuring the biophysical properties of single cells, such as mass, growth, and deformability. His research focuses on applying these technologies to address problems in cancer, immunology, and microbial systems. Manalis collaborates with various research groups, including the Shalek Lab, to link biophysical properties with gene expression at the single-cell level. He is also engaged in understanding the mechanisms governing growth heterogeneity and the role of circulating tumor cells in metastasis. He earned a B.S. degree in physics from the University of California, Santa Barbara in 1994 and a Ph.D. in applied physics from Stanford University in 1998. Manalis’s work is significant for developing new platforms to predict therapeutic responses by measuring biophysical properties of individual tumor cells, which could enhance treatment efficacy while minimizing toxicity in patients receiving cancer therapies.

Research Interests

Experience

Professor

1999-01-01 — Present

MIT • Cambridge, MA

Professor in the Department of Biological Engineering, focusing on microfluidic technologies.