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Scott Manalis is the David H. Koch (1962) Professor of Engineering and a faculty member in the Departments of Biological Engineering and Mechanical Engineering at the Massachusetts Institute of Technology (MIT). He currently serves as the Associate Department Head of the Department of Biological Engineering. He received his Bachelor of Science degree in Physics from the University of California, Santa Barbara, and his PhD in Applied Physics from Stanford University. Manalis is the founder of companies such as Travera and Affinity Biosensors, which utilize suspended microchannel resonators for weighing single cells. His research focuses on the development of novel instrumentation for cancer research, particularly in the areas of detection and monitoring, metastasis, and precision medicine. His laboratory develops quantitative real-time techniques for single-cell analysis, creates functional assays, and develops new technology platforms for predicting therapeutic response based on the biophysical properties of individual tumor cells. He collaborates with various research institutes, improving the understanding of circulating leukemia cell dynamics and identifying RNA-expression states that affect cancer drug susceptibility.