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Sean Megason is a Professor in the Department of Systems Biology at Harvard Medical School. His research focuses on using imaging-based systems biology to elucidate principles of animal development. Particularly, he is interested in long-standing problems in embryology that have resisted molecular reductionist approaches, including patterning, morphogenesis, and size control. The Megason Lab studies the inner ear and spinal cord of zebrafish, employing various techniques including genetics, microscopy, and modeling. They have pioneered the use of toto imaging, revealing the origins of biological form. By taking advantage of completed genome projects, the lab demonstrates how animals share similar sets of genes. They capture dynamic biological information across multiple scales, utilizing high-resolution timelapse confocal and two-photon microscopy to generate extensive image datasets. His work combines toto imaging with mathematical and computational modeling to elucidate the multiscale principles that control developmental processes in zebrafish. Sean's contributions aim to enhance understanding of the mechanistic principles linking genes to the complex organization of embryos.
Harvard Medical School • Boston, MA
Leading research in imaging-based systems biology and animal development.
Administered by the Division of Medical Sciences (DMS). GRE is not required and will not be considered for BBS, Immunology, and Neuroscience.