Dr. Serge Przedborski

Biography

Serge Przedborski is a prominent researcher focusing on the molecular and cellular biology of neurodegenerative disorders, particularly Parkinson's disease (PD) and Amyotrophic Lateral Sclerosis (ALS). His ongoing research aims to elucidate the contributions of both cell-autonomous and non-cell-autonomous mechanisms to neurodegeneration, utilizing toxic and genetic experimental models of these diseases. A significant aspect of his laboratory's work investigates alterations in mitochondrial biology, with a specific emphasis on mitochondrial dynamics and mitophagy, which provoke degeneration in certain subpopulations of neurons. Additionally, his team explores the mechanisms by which non-neuronal cells, such as microglia and astrocytes, influence neuronal demise in the context of PD and ALS. Przedborski's research is well-supported by various federal grants and private agencies, underscoring the relevance and impact of his work in understanding the complexities of neurodegeneration. He serves as a Senior Editor for the Journal of Neuroscience and is an Associate Editor for Movement Disorders. His contributions have established him as a leading figure in the field, with a commitment to advancing knowledge in neurobiology and disease.

Research Interests

Experience