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Shan Zha is the James Wolff Professor at Columbia University, where he specializes in Pathology, Cell Biology, Microbiology, and Immunology within the Herbert Irving Comprehensive Cancer Center. His research focuses on the investigation of defects in DNA repair and the DNA damage response and their impact on normal immune system development and lymphomagenesis. Zha's lab is known for developing cutting-edge technologies such as high-throughput translocation sequencing, single-cell sequencing, multi-color flow cytometry, and CRISPR-based depletion and activation screens. The lab utilizes an extensive collection of sixty-five unique mouse models to better understand the structural and functional aspects of DNA damage response factors. Through his research, Dr. Zha aims to uncover new insights into treatment responses and invite committed young scientists to participate in advancing these investigations.
Department of Anthropology (GSAS)