Dr. Sherman Weissman

Biography

Sherman Weissman is a Sterling Professor at Yale School of Medicine, specializing in Genetics. His research includes genomics scale analyses using genomic tiling arrays to map sites of transcription factor binding and studying mRNA expression patterns in the hematopoietic and immune systems. He examines differentiation responses in neutrophils and monocytes to stimuli and has planned similar studies in dendritic cells. His work involves genome-wide mutation detection and the development of novel approaches for identifying somatic mutations in neoplasias. Collaborating with Professor M. Snyder at the Yale Center for Genomics, he focuses on detecting deletions and inversions in genomes with unprecedented sensitivity and accuracy. Weissman's research also encompasses protein expression patterns in hematopoietic cells, complementing his genomic studies. He is particularly interested in genes associated with the major histocompatibility complex and their roles in the immune system, as well as mutations related to Werner syndrome, a disorder that resembles premature aging. His research contributes significantly to understanding complex gene regulation and immune responses.

Research Interests

Experience