Dr. Shu Ou Shan

Professor

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Biography

Shu-ou Shan is a Professor of Chemistry at the California Institute of Technology, where he focuses on molecular machines, protein folding, and quality control mechanisms. He earned his B.S. in 1994 from the University of Maryland and his Ph.D. from Stanford University in 2000. His research utilizes mechanistic enzymology combined with biophysical tools such as fluorescence spectroscopy and single-molecule fluorescence microscopy to elucidate the molecular basis of protein biogenesis pathways. A particular area of expertise includes the engineering of molecular chaperones to understand their role in preventing protein misfolding and aggregation, which can lead to neurodegenerative disorders. Professor Shan's lab integrates various approaches to develop quantitative models that explain the dynamics of protein synthesis and folding in cells.

Research Interests

Experience

Professor

— Present

California Institute of Technology • Pasadena, CA

Teaching and conducting research in chemistry, focusing on molecular biogenesis and protein folding mechanisms.

Assistant Professor

— Present

California Institute of Technology • Pasadena, CA

Engaged in teaching and research in the field of chemistry.

Courses

Macromolecular Function: Kinetics, Energetics, Mechanisms Advanced Topics in Biochemistry and Biophysics

Requirements for California Institute of Technology

Doctorate Program
Requirements
TOEFL
Total
Required:100
IELTS
Overall
Required:7
Prerequisites
Bachelor's degree or equivalent Strong background in mathematics and physical sciences
Application Checklist
  • Online Application
  • Statement of Purpose
  • Three Letters of Recommendation
  • Transcripts
  • Resume/CV
Specialization Notes

Most Caltech graduate programs are PhD-only. GRE General and Subject tests vary by department; many have made them optional or no longer accept them.