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Silvi Rouskin is an Assistant Professor at Harvard Medical School in the Department of Microbiology. Her research focuses on the structure and function of RNA, particularly in relation to gene expression regulation and disease states, including viral infections and neurodegeneration. Rouskin investigates co-transcriptional RNA folding and alternative splicing and aims to model cell-type-specific and disease-specific alternative splicing on a genome-wide scale. Her lab employs innovative methods, including the use of dimethyl sulfate (DMS) to study RNA modifications and high-throughput sequencing to understand RNA structures that influence gene expression. Notably, her research on Human Immunodeficiency Virus-1 (HIV-1) RNA and its structural properties reveals crucial insights into the mechanisms of alternative splicing and viral gene regulation. Recently, the lab has shifted focus to exploring the structural complexities of the SARS-CoV-2 genome. Rouskin's work is aimed at providing a deeper understanding of RNA and its roles in diverse biological processes.
Administered by the Division of Medical Sciences (DMS). GRE is not required and will not be considered for BBS, Immunology, and Neuroscience.