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Simon L. Dove is an Associate Professor in the Microbiology Department at Boston Children's Hospital, specializing in the study of the regulation of gene expression in pathogenic bacteria, including Pseudomonas aeruginosa. His research focuses on the roles of transcription and post-transcriptional regulators, specifically investigating how virulence genes are regulated in bacterial pathogens. His current work examines the RNA-binding protein Hfq and its interactions with various RNA species, revealing its importance in controlling gene expression and bacterial responses to environmental cues. Dove's laboratory has developed methods for studying RNA-binding protein interactions with nascent transcripts, contributing to a greater understanding of bacterial regulatory networks and the intricacies of post-transcriptional control. He is also engaged in exploring metabolic regulators in Francisella tularensis, shedding light on the survival mechanisms of this organism.
Boston Children's Hospital • Boston, MA
Specializes in microbiology with a focus on pathogenic bacteria and gene regulation.
Administered by the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences (GSAS).