Generate a tailored SOP for Dr. Simon Newstead. Improve your application with a focused, well-structured draft.
Prof. Simon Newstead holds the David Phillips Chair in Molecular Biophysics at the University of Oxford. His research group is dedicated to understanding the function of nutrient transporters at the molecular level, specifically focusing on membrane proteins that are crucial for nutrient uptake and drug transport. The work presents significant medical advantages, especially in delineating the pharmacokinetic properties of administered drugs. Newstead’s group employs a variety of biophysical and biochemical methods, with a significant emphasis on structural biochemistry. Key techniques utilized by the group include protein crystallization and single particle cryo-EM imaging. They currently focus on families of secondary active SLC transporters that are associated with drug transport, which includes the SLC15 peptide transporters (PepT1 and PepT2), and various amino acid (SLC7, 36, 38) and nucleotide sugar transporters (SLC35) families. Newstead’s research aims to provide in-depth insights into the structural and functional aspects of these transporters, contributing to a better understanding of their regulation and biochemistry.
Department of Politics and International Relations - Higher Level English requirement.