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Simon Thebault is a neurologist specializing in multiple sclerosis (MS) and neuroimmunology. His research focuses on developing and translating actionable soluble immune cell biomarkers to improve patient outcomes. Bridging the gap between laboratory innovation and clinical care, his lab employs advanced detection technologies and multiomic approaches to analyze biospecimens and well-characterized clinical cohorts. Key research areas include validating the clinical utility of emerging serum biomarkers such as neurofilament light chain and glial fibrillary acidic protein, characterizing cerebrospinal fluid protein and immune cell profiles as indicators of central nervous system-compartmentalized inflammation, and investigating the role of Epstein-Barr virus in priming disease activity in MS, exploring its potential as a biomarker and therapeutic target.
Department: Department of Medicine. Program: Experimental Medicine.