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Simona Huwiler focuses on predatory bacteria and their potential as novel therapeutic agents. Her research investigates the molecular mechanisms of predatory bacteria, specifically Bdellovibrio bacteriovorus, which plays a significant role in degrading pathogenic gram-negative bacteria, especially antibiotic-resistant strains. By exploring the predatory lifecycle of Bdellovibrio bacteriovorus, her group employs systems approaches, utilizing synthetic biology to manipulate this bacterium for therapeutic purposes. Their work includes generating high-quality proteomes and holistic metabolomes from the bacteria it degrades, allowing for a detailed understanding of the predatory process. This research not only sheds light on the ecological importance of predatory bacteria in the microbial ecosystem but also presents innovative strategies for harnessing these microorganisms as 'living antibiotics' to tackle bacterial infections.
Department of Law