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Smita K Nair is a seasoned T cell immunologist with over 22 years of experience in the field of cancer vaccines and immunotherapy. She holds professorships in Surgery, Pathology, and Neurosurgery at Duke University and is a member of the Duke Cancer Institute. Nair's research focuses on innovative approaches to cancer treatment, including dendritic cell vaccines utilizing tumor-antigen encoding RNA, local immune receptor modulation, and combination therapies that integrate cytotoxic treatments with dendritic cell-based vaccines and immune checkpoint blockade. Furthermore, her work includes adoptive T cell therapy using chimeric antigen receptors and direct injections of tumor antigen encoding RNA, utilizing advanced techniques such as nanoparticles and aptamers. Throughout her career, she has been awarded numerous research grants, aiming to explore the immune responses in cancer therapy and improve therapeutic strategies against cancer metastasis. Nair has an extensive publication record that reflects her contributions to the understanding of immune dynamics in cancer and the development of targeted immunotherapeutic approaches.
Duke University • Durham, NC
Leading research and clinical initiatives in immunology and cancer therapy.
Duke University • Durham, NC
Focused on cancer immunotherapy techniques and program development.
Duke University • Durham, NC
Conducted research on T cell biology and therapeutic applications.
Duke University • Durham, NC
Contributed to experimental surgical research and immunology.
Department of Biomedical Engineering (MS program)