Dr. Sourav Ghosh

Biography

Sourav Ghosh, Ph.D. obtained his M.Sc. in Zoology from the University of Calcutta, where he studied Drosophila mosquito genetics. He then completed his graduate studies on cell cytoskeleton protein trafficking under John V. Cox at the University of Tennessee, Memphis. Following this, Dr. Ghosh conducted postdoctoral research on cell signaling at the Salk Institute for Biological Studies under the guidance of Tony Hunter. In 2007, he joined the University of Arizona as an Assistant Professor. In 2014, he moved to Yale University School of Medicine where he currently serves as a Professor. Alongside Dr. Carla Rothlin, he co-directs a lab focused on studying the regulation of inflammation, a critical feature of immune defense. Their work addresses the 'Goldilocks Principle' of inflammation, which asserts the importance of the appropriate amplitude and duration of inflammatory responses. Drs. Rothlin and Ghosh investigate the molecular mechanisms that negatively regulate inflammation, aiming to ensure that the response is neither excessive nor inadequate. Disruptions in these molecular circuits can lead to a variety of clinical issues, including chronic pathological inflammation, autoimmunity, and impaired wound healing, with the potential to harness these pathways for improved anti-cancer immunity.

Research Interests