Dr. Srijan Sen

Biography

Srijan Sen is a Professor in the Department of Psychiatry and a Research Associate Professor at the Molecular & Behavioral Neuroscience Institute at the University of Michigan. He also serves as a Faculty Associate within the Department of Psychology. His research focuses on the interactions of biological factors with stress and their impact on the development of depression. He is particularly interested in predicting the onset of stress, which varies greatly among individuals, and aims to overcome barriers in this area by utilizing a medical internship model. This model provides a unique opportunity to study prospective stressors that can be uniformly predicted during medical training. Sen's work involves identifying genes associated with depression through genome-wide association and coding exome studies, based on a sample of 10,000 interns. He examines how psychological factors and epigenetic patterns, alongside serum protein levels, can moderate the relationship between stress and depression. His significant publications in the field highlight his contributions to understanding depression among resident physicians and the use of cognitive behavioral therapy to prevent suicidal ideation among medical interns.

Research Interests