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Srinivasa Reddy's laboratory at UCLA studies physiological and pathological phenomena mediated by arachidonic acid (AA) metabolites, which are implicated in various disease processes such as acute and chronic inflammation, cardiovascular disease, and cancer. His team is currently investigating the role of oxidized phospholipids in gene expression and the interaction of monocytes with endothelial cells, focusing on the genes required for these processes, particularly MAP-Kinase Phosphatase-1 (MKP-1) in the context of atherosclerosis. The lab has developed animal models to study the effects of Paraoxonase proteins in atherosclerosis and the anti-atherogenic properties of HDL-associated enzymes. Reddy's work also explores the role of COX-2 in vascular biology and inflammation, including the implications of COX-2 selective inhibitors. His research contributes to the understanding of inflammatory disorders and cardiovascular diseases, with a focus on developing novel therapeutic strategies.
Department of Economics admits primarily for the PhD program.