Dr. Stefan Ståhl

Biography

Stefan Ståhl is a Professor at Kungliga Tekniska Högskolan (KTH) in the Department of Protein Science, where he also serves as the Deputy Head of the Department. His research focuses on Protein Engineering, particularly on small affinity domains known as affibody molecules, and their applications in medicine, medical imaging, and drug development. He has been involved in developing these small affinity proteins within his department, utilizing staphylococcal proteins as scaffolds to construct combinatorial libraries to select affibody binding proteins for desired target proteins. His work includes the use of technology platforms that enable the generation of affibodies as part of his research focus, as well as the evaluation of protein libraries through fluorescence activated cell sorting (FACS) for screening. Professor Ståhl's research extends to investigating the therapeutic potential of affibody molecules in settings such as tumor targeting and imaging for biotherapy applications. His studies have explored cancer biomarkers including EGFR, HER2, and HER3 in various tumor targeting contexts. Additionally, he investigates affibodies in relation to neurodegenerative disorders such as Alzheimer's and Parkinson's disease. His aim is to develop tools for studying disease progression, generate tracers for medical imaging, and create candidates for therapeutic proteins in preclinical models.

Research Interests

Courses