Dr. Stephanie Willerth

Biography

Stephanie Willerth is a Professor in the School of Medical Sciences and Mechanical Engineering at the University of Victoria. Her research focuses on developing stem cell-based bioengineering approaches to address significant biological problems in areas such as tissue engineering and regenerative medicine. Her lab works to reproducibly engineer neural tissue from pluripotent stem cell lines under strict regulation conditions. They investigate the neural differentiation process and devise bioactive scaffolds that guide stem cell differentiation using various physical and chemical cues. Willerth's team also delivers chemical signals through specially designed scaffolds that enable controlled drug release over extended periods. Furthermore, she explores the mechanisms of differentiation using next-generation DNA sequencing to analyze differences in transcription patterns in stem cells as they differentiate. The ultimate aim of her research is to develop engineered tissues suitable for transplantation into the human nervous system to treat diseases like Parkinson's and to repair damaged tissue in the spinal cord to promote recovery and restore lost functions.

Research Interests