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Stephen Elledge is the Gregor Mendel Professor of Genetics at Harvard Medical School. His research focuses on how eukaryotic cells sense and respond to stress, particularly in relation to DNA damage and genetic material integrity. He has made significant contributions by identifying key proteins and kinases involved in the DNA damage response, aiding in the understanding of genomic instability and its link to cancer. Through genetic screens, he identified several new genes related to DNA damage and cancer resistance, including those involved in the tumor suppressor pathway of senescence. Furthermore, Elledge has developed innovative genetic technologies, such as ORF and shRNA libraries, enhancing the ability to explore human diseases. His work has led to the discovery of new tumor suppressors and potential drug targets, emphasizing the importance of systems analysis in understanding cancer biology.
Administered by the Division of Medical Sciences (DMS). GRE is not required and will not be considered for BBS, Immunology, and Neuroscience.