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Stephen P. Goff is a distinguished professor at Columbia University, specializing in Biochemistry and Molecular Biophysics. He has a significant academic history with a PhD from Stanford University Medical Center and a fellowship at the Massachusetts Institute of Technology. His laboratory focuses on mammalian retroviruses, including the study of viral gene products and host protein interactions. Goff's research highlights the viral life cycle's complexity, addressing retroviral replication and the mechanisms behind host restriction. His lab has made crucial discoveries, such as the ZAP zinc finger antiviral protein, which is essential in degrading viral mRNAs, thereby inhibiting virus replication. Additionally, Goff has contributed to the understanding of chromatin modification in response to retroviral DNA during acute infections. Over his career, he has trained numerous PhD students and postdoctoral fellows, many of whom now hold prominent academic and research positions globally. His extensive publication record is accessible via his Google Scholar profile, reflecting his impact in the field of virology and immunology.
Department of Anthropology (GSAS)