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Stephen Holgate is a Medical Research Council Clinical Professor of Immunopharmacology at the University of Southampton, UK. He completed his medical training in London and spent 2 years at Harvard Medical School to acquire skills in allergic disease mechanisms. Upon returning to Southampton in 1980, he established a research group focused on the mechanisms of asthma and has since contributed significantly to understanding allergic respiratory diseases, asthma, and COPD. His work involves innovative approaches that span epidemiology, genetics, pathology, microbiology, immunology, pharmacology, and experimental medicine, ultimately guiding asthma management and identifying novel therapeutic targets. Notable contributions include elucidating the role of mast cells in asthma, the impact of respiratory viruses and air pollution on asthma exacerbation, and the discovery of the asthma susceptibility gene ADAM33. Holgate's extensive research has led to over 1,000 peer-reviewed publications, with a focus on stratified medicine. His leadership roles include past President of the British Society for Allergy and Clinical Immunology and contributions to various health authorities. Holgate's ongoing research is pivotal in spearheading precision medicine approaches towards chronic respiratory diseases.
University of Southampton • Southampton, England
Leading research in immunopharmacology, focusing on asthma and COPD.