Dr. Stephen Mayo

Professor

Build a Statement of Purpose

Generate a tailored SOP for Dr. Stephen Mayo. Improve your application with a focused, well-structured draft.

Biography

Stephen L. Mayo is a leading researcher in the field of protein design and computational biology. He has a distinguished career at the California Institute of Technology where he holds the position of Bren Professor of Biology and Chemistry and the Merkin Institute Professor. His research primarily focuses on protein design, structure, and stability, applying both theoretical and experimental techniques to understand and manipulate biological macromolecules. Mayo’s work emphasizes the development of quantitative methods for protein design, exemplified by his systematic approach called 'protein design automation,' which has led to significant advancements in enzyme design and the creation of novel catalysts. In addition to his work on enzyme catalysis, he investigates protein sequence evolution and the mechanisms of protein-protein recognition, aiming to elucidate how proteins interact with each other at the molecular level. His innovative computational procedures enable the exploration of neutral mutational pathways that can inform future protein design strategies. Mayo has received numerous accolades for his contributions to the field, reflecting the impact of his research on both academia and industry.

Research Interests

Protein Design Computational Protein Design Structural Biology Protein Evolution Protein-Protein Recognition

Experience

Bren Professor

2007-01-01 — Present

California Institute of Technology • Pasadena, CA

Leader in research and education within the realm of biology and chemistry.

Professor

2003-01-01 — 2007-01-01

California Institute of Technology • Pasadena, CA

Conducted advanced research and oversaw departmental education.

Associate Professor

1998-01-01 — 2003-01-01

California Institute of Technology • Pasadena, CA

Focused on advanced studies in protein design.

Assistant Professor

1992-01-01 — 1998-01-01

California Institute of Technology • Pasadena, CA

Initiated academic career, conducting research in biochemistry.

Senior Research Fellow

1991-01-01 — 1992-01-01

California Institute of Technology • Pasadena, CA

Conducted research in chemical engineering and protein design.

Requirements for California Institute of Technology

Doctorate Program
Requirements
TOEFL
Total
Required:100
IELTS
Overall
Required:7
Prerequisites
Bachelor's degree or equivalent Strong background in mathematics and physical sciences
Application Checklist
  • Online Application
  • Statement of Purpose
  • Three Letters of Recommendation
  • Transcripts
  • Resume/CV
Specialization Notes

Most Caltech graduate programs are PhD-only. GRE General and Subject tests vary by department; many have made them optional or no longer accept them.