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Originally from New York, Professor Tannenbaum began his scientific education at MIT, earning a Bachelor of Science in Food Technology. He subsequently earned a PhD in Food Science and Technology, with a minor in Chemistry, also at MIT. Tannenbaum joined the MIT faculty in the Department of Nutrition and Food Science, which later evolved into the Department of Biological Engineering. His research interests include the formation, distribution, and metabolism of nitrate, nitrite, and N-nitroso compounds, which have significant implications for health and disease. The Tannenbaum lab's work has led to the discovery of endogenous synthesis of nitrogen oxides, particularly the biological significance of nitric oxide. Current research focuses on the pathophysiological consequences of nitric oxide oxidation products, cell-mediated nitrosation, free-radical reactions, and the genotoxic effects of chemical damage to DNA. The group is also investigating the protective effects of antioxidants against oxidative stress as well as applications in tissue engineering, drug development, and chemical toxicity. Tannenbaum's laboratory has developed innovative in vitro organized tissue-based sensors for rapid screening of drug metabolism and detection of unknown toxins.
Massachusetts Institute of Technology • Cambridge, MA
Professor Emeritus in the Department of Biological Engineering, with a focus on research related to chemical toxicity and biochemical transformations.