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Struan F.A. Grant is a Professor of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania and holds the Daniel B. Burke Endowed Chair in Diabetes Research at the Children's Hospital of Philadelphia. With over 25 years of experience in human genomics, he has made significant contributions to the field, including the discovery of polymorphic Sp1 site at the COL1A1 gene associated with osteoporosis and the identification of variation in the TCF7L2 gene, which plays a critical role in conferring risk for type 2 diabetes. As the Director of the Center for Spatial Functional Genomics, his current research focuses on investigating disease genomics with an emphasis on pediatric health. He utilizes high-throughput genotyping and sequencing technologies, alongside bioinformatic approaches, to address genomic challenges related to childhood obesity, bone strength, and diabetes. His work aims to unravel the complex genetic factors influencing these traits, which are heavily influenced by environmental interactions, particularly in children. Grant's leadership in international genetics efforts has garnered widespread recognition, underscoring his commitment to expanding the understanding of genetic determinants of health in children.
Perelman School of Medicine, University of Pennsylvania • Philadelphia, PA
Teaching and conducting research in Pediatrics and Genetics.
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