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Sui Huang, MD, PhD, is an Associate Professor at the Feinberg School of Medicine, Northwestern University. His research lab focuses on understanding the structure and function of nuclear organelles, particularly nucleoli and perinucleolar compartments (PNC), in both normal and disease states, especially in cancer. He conducts translational research that utilizes specific nuclear features as phenotypic markers to aid in the development of anti-cancer drugs. The lab explores the complex role of single genes in cancer, emphasizing that cancer is a highly heterogeneous multi-step transformation process. Current efforts are directed at understanding the mechanisms necessary for cancer metastasis and using tools like metarrestin, which has shown selective properties against cancer metastasis in xenograft models, to enhance survival rates in tumor-bearing animals. His work aims to identify small molecules that can effectively target multiple relevant processes in cancer metastasis, utilizing the unique nuclear characteristics present in cancer cells.
Northwestern University Feinberg School of Medicine • Chicago, Illinois
Conducting research on the structure and function of nuclear organelles
Administered by The Graduate School; focuses on Biomechanics, Imaging, Biomaterials, and Regenerative Medicine.