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Sunny Shin is a Professor in the Department of Microbiology at the Perelman School of Medicine, University of Pennsylvania. Her research lab focuses on innate immune mechanisms that help host organisms defend against bacterial pathogens and how these pathogens evade host immunity to cause disease. Dr. Shin's team studies various gram-negative bacteria, including intracellular pathogens like Legionella pneumophila and Coxiella burnetii, as well as extracellular pathogens. Their research is particularly focused on how the immune system distinguishes between virulent and avirulent bacteria, tailoring appropriate antimicrobial responses. A significant aspect of her work involves understanding the inflammasome pathway and its role in mediating host defense responses. Dr. Shin's laboratory aims to elucidate mechanisms that enhance our understanding of bacterial pathogenesis and improve the design of effective antimicrobial therapies and vaccines. She encourages prospective students and postdoctoral researchers to reach out regarding research opportunities in her lab.
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