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Susan Howlett is a Professor in the Department of Pharmacology at Dalhousie University. Her research focuses on cardiac contraction regulation in health and disease, notably the differences in male and female heart cell functionality as affected by age and overall health. She has played a pivotal role in creating the frailty index, which measures frailty in aging animals, providing a significant advance for translating scientific discoveries in aging research into practical clinical interventions. Her work has been published in numerous prestigious journals, contributing to the understanding of mechanisms involved in myocardial ischemia and the hormonal regulation of cardiac function. Dr. Howlett's research interests encompass aging, frailty, hormonal regulation of cardiac function, estrogen and testosterone dynamics, as well as cardiac excitation-contraction coupling.