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Susan Martinis is a Professor in the Department of Biochemistry at the University of Illinois. Her research focuses on enzymology, molecular evolution, and specifically RNA biology. She investigates RNA structure and function, RNA-protein interactions, and the mechanisms of biological reactions. A key area of her work is on tRNA synthetases, which are essential enzymes responsible for attaching amino acids to the correct tRNA during protein synthesis. Martinis's research aims to understand the fidelity of tRNA synthetases and their editing mechanisms, as errors in this process can lead to protein misfolding and associated diseases. She employs biochemical, structural, and genetic techniques to elucidate the molecular interactions that dictate the specificity and activity of these enzymes. Additionally, her work explores the evolutionary significance of tRNA synthetases beyond protein synthesis, including their roles in mitochondrial intron splicing. Martinis holds a B.S. from Washington State University and a Ph.D. from the University of Illinois.
Department of Biochemistry • University of Illinois
Professor focused on enzymology and RNA biology.
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