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Susan L. Smith is a Professor in the Department of Cell Biology and the Department of Pathology at NYU Grossman School of Medicine. Her research focuses on the mechanisms of DNA replication and segregation, which are crucial for maintaining genome integrity. Errors in these processes can lead to aneuploidy, severely impacting human growth and leading to the development of cancer in somatic cells. Dr. Smith's work emphasizes the importance of telomeres, the ends of eukaryotic chromosomes, and their unique protective mechanisms, particularly the role of shelterin, a six-subunit telomere-binding complex, in regulating telomere function in normal cells, stem cells, aging, and cancer. She aims to understand how accessory factors associated with shelterin influence telomere structure and function, control access to telomerase, and mediate sister chromatid cohesion. Her long-term goal is to elucidate the mechanisms that ensure genome integrity and cell survival.
Open Program in Biomedical Sciences (Vilcek Institute) covers departments like Biochemistry, Pathology, Neuroscience, Microbiology, etc.