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Sylvie Mader is a full professor at the University of Montreal, in the Faculty of Medicine, within the Department of Biochemistry and Molecular Medicine. Her research focuses on the mechanisms controlling cellular differentiation and proliferation, influenced by various extracellular molecular signals acting through membrane and intracellular receptors. Her work particularly emphasizes steroid hormones, like estrogens, that traverse cell membranes to interact with nuclear receptors, acting as hormone-dependent transcription factors. Mader's research investigates the effects of estrogens and anti-estrogens, such as tamoxifen, on cell growth and gene expression regulation, utilizing cell lines derived from breast and uterine tumors. Identifying the target genes of these hormones is vital for developing new therapeutic strategies against breast and uterine cancers. Her expertise encompasses bioinformatics, genomics, proteomics, and the molecular signaling cascades involved in tumorigenesis.
University of Montreal • Montreal, QC, Canada
Lead research projects focusing on the role of estrogens and anti-estrogens in cancer.
Most programs require French B2 level; specific departments may require C1 or C2.