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Dr. Takayuki Nagasaki is an Assistant Professor in the Department of Ophthalmic Science at Vagelos College of Physicians and Surgeons, Columbia University. His research is focused on understanding the biology of the anterior segment, particularly the molecular and cellular mechanisms involved in the management of injuries and diseases affecting the cornea and conjunctiva. His laboratory pursues several key questions related to ocular surface stem cells—specifically, the distribution, movement, turnover, and differentiation of epithelial stem cells in the cornea and conjunctiva. Through the use of modern cell biological techniques, including in vivo time-lapse fluorescence microscopy, hyperspectral imaging, and computer-assisted modeling, Dr. Nagasaki aims to dissect the underlying mechanisms that maintain normal corneal epithelium and repair damaged tissue. His research also addresses the triggers of blood vessel growth in the cornea, a potential condition leading to blindness. Dr. Nagasaki’s work is characterized by a blend of experimental and analytical approaches, striving to understand basic biological questions while applying them to clinical issues in ocular health.
Exact Department Name: Department of Physiology and Cellular Biophysics. Program: Cellular and Molecular Physiology & Biophysics.