Dr. Tayyaba Ishaq

Biography

Tayyaba Ishaq is a Postdoctoral Associate at the Yale School of Medicine. She holds an MPhil in Human Genetics from the University of the Punjab, where she explored genetics related to skeletal dysplasia, focusing on the purification of human proteins using nickel chromatography. In her current role, she supports research under the supervision of Professor Sadaf Naz, with emphasis on the purification of biologics such as ENPP1, an enzyme crucial for regulating ectopic calcification and bone mineralization, as well as DNase1 for treating pathologies associated with the aberrant formation of neutrophil extracellular traps through netosis. Additionally, she is involved in generating antibodies in mice against the antigen MPO and is engaged in a large-scale study using a murine model of Chronic Kidney Disease (CKD). With a strong foundation in medical research and various diagnostic and therapeutic techniques, her work primarily addresses bone diseases and musculoskeletal abnormalities.

Research Interests

Experience