Dr. Teresa Palomero

Biography

Teresa Palomero is a professor of Pathology and Cell Biology at Columbia University, where she conducts extensive research on the genetic mechanisms underlying T cell malignancies. Her work focuses primarily on the Institute of Cancer Genetics, where she has significantly contributed to the field of human T-cell leukemia and lymphomas by integrating genomic technologies with experimental therapeutics. Dr. Palomero has played a pivotal role in identifying new oncogenes and tumor suppressor genes, defining their mechanisms of action, and translating this knowledge into novel targeted therapies. She is recognized for her cutting-edge research, particularly in the area of Peripheral T-cell Lymphoma (PTCL), where her group employs whole exome sequencing, gene expression profiling, and single-cell sequencing to unveil novel drivers of tumor evolution. Among her notable discoveries are mutations in RHOA and FYN as critical drivers of Angioimmunoblastic T-cell lymphoma. Dr. Palomero has also pioneered the development of genetically engineered mouse models to further explore these mechanisms and evaluate the impact of targeted therapies on T-cell lymphoma. Her contributions have been instrumental in advancing our understanding of T-cell tumor biology and potential treatment strategies.

Research Interests

Experience